No serious adverse events were reported.41. Subscribe to newsletters for the latest medication news, new drug approvals, alerts and updates. Information regarding safety and efficacy in pregnancy and lactation is lacking. In the event of an essential oil, poisoning calls Poison Control immediately. National Association for Holistic Aromatherapy’s Code of Ethics. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. May Aid Diabetes Treatment. Microbial metabolites of RA may account for many of its activities. The Eastern Mediterranean region, Western Asia, Southern Europe, Caucasus, and northern Iran are considered its areas of origin, but it grows worldwide. LBEO, widely used in the pharmaceutical and food industries, is considered to be responsible for lemon balm’s antibacterial and antifungal effects. Microbial metabolites of RA may account for many of its activities. While animal studies support lemon balm’s use as an antidepressant, studies to date used doses so large as to be unfeasible for clinical use. The Bacopa monniera herb, also known as Brahmi, has been, Whether you are collecting the flowers, leaves or stems, you, With its bright green stalks and vibrant, lavender-pink and spiky, As winter slowly winds down, many gardeners cannot wait to, There’s good news for sufferers of upper respiratory ailments. Poison Control operators assist families with thousands of essential oil poisonings every year and are well equipped to advise you on necessary actions to take after a poisoning. Available for Android and iOS devices. Care should be exercised with regard to high dosage or prolonged use until in-depth evidence from toxicity and dose-escalation studies are available. Paracelsus (1493-1541) prescribed lemon balm for nervous system disorders. A small trial evaluated the cardiac effects of lemon balm and reported possible cardiac muscarinic receptor stimulation or calcium channel-dependent blockage.38 Potentiation of pharmacologic agents may be possible. Lemon balm has been used in herbal medicine since the times of Pliny (Roman, AD 23-79), Dioscorides (Greek, AD 40-90), Paracelsus (Austrian 1493-1541), and John Gerard (English, 1545-1612). This product may be unsafe when used before surgery or other medical procedures. What Is Neroli Oil and What Is It Used For? Post was not sent - check your email addresses! He attributed its antidepressant effects to its aroma. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Lemon balm may exhibit glycemic control, as per studies. Rosmarinic acid was found to inhibit the C3 and C5 convertase steps in the complement cascade.27, 28, 29 This action may play a role in the anti-inflammatory action of Melissa extract, because the action was observed in vitro and in vivo in rats with oral administration of the compound. 21 WAYS TO CLEANSE AND ENERGIZE WITH LEMON OIL, Chemical Exposure Decreases with Change of Cosmetics, Discover Relieving Ways To Fortify With Rosemary Antioxidant CO2 Extract, Double Chamomile Chronic Pain Cream Recipe, Essential Oils in Alternative Acne Therapy, How Can Frankincense Oil Aid in Natural Skin Care, Natural Balms for Cuts, Stings, and Bruises, Queen of the Spices; Cardamom Health Benefits, Vodka Is the Secret to This Powerful DIY Deodorant, Our Organic Supplements, Healthy, Balanced Life, Uses, Chemistry, and Pharmacology of Lemon Balm, Herbal Hacks, Part 2: Crafts, Health, and Beauty, New Data on COVID-19 and Promising Research on Natural Medicines |, Not Just for Teatime: The Herbal Significance of Camellias, DIY Recipe of the Month: Cranberry Orange Bitters • The Organic Alcohol Company, Scientific Journal Publishes BAPP Staff-written Article Detailing Adulteration Schemes Used to Fool Commonly Used Laboratory Analytical Methods, Medicinal Plant Research Experts Publish Extensive Review on Adaptogens, BACOPA MONNIERA: Brain Health and Nervous System Restorer, Pantry Profile: Chives {Allium schoenoprasum}, 800 Reasons Turmeric Threatens Big Pharma | GreenMedInfo | Blog Entry, Healthy Lungs: Health Benefits of Chapparel, How To Guarantee Your Garden Starts Off On The Right Foot, DIY Recipe of the Month: Cranberry Orange Bitters • The Organic Alcohol Company – Story land, Medicinal Plant Research Experts Publish Extensive Review on Adaptogens – Glyn Hnutu-healh: History, Alchemy, and Me, Activities and Applications of Emerging Herbal Preparations, Herbs for Respiratory Health – Urban Moonshine, DIY Recipe of the Month: Spiced Pear Liquor • The Organic Alcohol Company, Free Webinar: Saw Palmetto: A Conversation on Sustainability, Quality, and Authentication, BACOPA MONNIERA: Brain Health and Nervous System Restorer, Pantry Profile: Chives {Allium schoenoprasum}, How To Guarantee Your Garden Starts Off On The Right Foot, Healthy Lungs: Health Benefits of Chapparel. Lovely and interesting writing. Research reveals little or no information regarding toxicology with the use of this product. $19.95 $ 19. In ADHD in children, researchers paired lemon balm with valerian root. There are few pharmacokinetic studies of lemon balm, with most focusing on its hydrocinnamic acid derivatives, especially RA, absorbed via paracellular diffusion. Flavonoids with glycosides of luteolin, quercetin, apigenin and kaempferol [ESCOP, 2003]. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Often said to ease stress and anxiety, lemon balm contains a compound known as rosmarinic acidthat appears to have potent antioxidant and antimicrobial properties. It is a component of about 400 ITM medicinal preparations. The American Association of Poison Control Centers hotline is available 24 hours a day, 7 days a week at 1-800-222-1222. Many flavonoids, including flavones, flavanones, flavonols, and flavanols, are found in lemon balm, with numerous biological effects. In vitro studies reveal lemon balm’s inhibition of several human cancer cell lines, but a great deal of research needs to be conducted before any clinical applicability could be assessed. Lemon Balm Leaf; Lemon balm tincture taken daily and lemon balm cream applied topically long-term, improved quality of life and decreased dementia ratings in seniors in two separate studies (Akhondzadeh et al., 2003; Ballard et al., 2002). Lemon balm, also commonly known as balm and bee balm, is a perennial lemon-scented herb. The small yellow or white flowers are attractive to bees and other insects. Future research needs include mechanisms of action, efficacy, and proper dosages for other ethnomedical uses of lemon balm, as well as proof-of-concept clinical trials evaluating its usefulness as an adjunct to conventional treatment for depression. Antidepressive effects of lemon balm need more study, especially the monoamine oxidase A (MAO-A) inhibitory activity of compounds other than RA. Lemon balm is said to soothe symptoms of stress, help you to relax, and … Scientific Name(s): Melissa officinalis L.Common Name(s): Balm, Lemon balm, Melissa, Sweet balm. The main triterpenes in lemon balm are ursolic and oleanolic acids, with reported biological effects including antifungal, cytotoxic, and hemolytic activities. Lemon balm (Melissa officinalis L.), also known as balm, English balm, garden balm, balm mint, common balm, melissa, sweet balm, heart’s delight, is an aromatic herb from the mint family (Lamiaceae). It is indigenous to the Mediterranean region and western Asia, and widely naturalized in Europe, Asia, and North America. Essential oils made from lemon balm leaves contain plant chemicals called terpenes, which play at least some role in the herb's relaxing and antiviral effects. A novel pharmacological mechanism of action for the anxiolytic botanical Melissa officinalis L. (lemon balm) is reported. Traditional uses of lemon balm have been supported by its pharmacological anxiolytic effects, possibly due to gamma-aminobutyric acid transaminase (GABA-T) inhibition and/or reduced levels of corticosterone. Myrrh Oil; USES OF MYRRH – PURIFICATION, PERFUMERY & MORE! While its composition varies by region and climate, most studies report that LBEO contains oxygenated monoterpenes, including the citral isomers geranial and neral, as well as citronellal, geraniol, and geranyl acetate. Its medicinal properties were first documented by Dioscorides (40-90 CE), who recommended a leaf decoction for spider, scorpion, and dog bites, and for amenorrhea, dysentery, mushroom poisoning, scrofulous tumors, and other indications. Lemon balm is high in flavonoids, which can have an antioxidant effect. Plants are a rich source of phytochemicals that have a variety of pharmacological activities. Lemon balm’s cardiovascular, cytotoxic, anti-inflammatory, antinociceptive, hypoglycemic, hypolipidemic, antioxidant, antimicrobial, antiviral, antispasmodic, antiangiogenic, and antiepileptic effects all have support in various research models, with the general proviso that many doses used in animal trials cannot realistically be applied in clinical practice. Thank you for reading the posts and you are welcome. The volatile oil of the plant had much weaker activity or was inactive in the same assays. You can also grow lemon balm yourself. It is a native of Europe and central Asia, and is now cultivated in most temperate and subtropical regions all over the world. No significant differences were found between groups in total cholesterol (TC), high-density lipoprotein (HDL), LDL:HDL, TC:HDL, fasting blood sugar, triglycerides, ALT, creatinine, body mass index, or physical activity. Disclaimer: All information contained on this website is for educational and informational purposes only and is based on traditional usage and research articles. Herbal Pharmacology Herbal Pharmacology. The plant has also been reported to be used as a cardiac and gastric tonic, memory enhancer, wound disinfectant, and for certain eye diseases. Crude lemon balm herb is typically dosed at 1.5 to 4.5 g/day. Lemon balm contains substances called tannins, which may be responsible for many of the herb's antiviral effects. It's been used safely in research for up to 4 months. It's POSSIBLY SAFE in adults when taken by mouth or applied to the skin in medicinal amounts, short-term. It contains … Antioxidant and antimicrobial effects also are attributed to its triterpenes. Since 2014, Crooked Bear Creek Organic Herbs Has Become The Forefront In Herbal Knowledge. Lemon balm supplements are widely available and are inexpensive; you can use the study above, 300 to 600mg daily, as a guideline. A standardized preparation of lemon balm (80 mg) and valerian extract (160 mg) has been given 2 or 3 times/day as a sleep aid, and has also been studied in children. Lemon balm is a lemony plant that’s commonly used in teas and seasonings. [1] Bonus: It can help you feel less stressed without making you feel sleepy or drugged—and that can mean better energy to enjoy your better mood. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. It can help relieve stress. To make lemon balm tea, follow these simple steps. None well documented. [email protected] Melissa officinalis L. (Lamiaceae) (lemon balm) is used in folk medicine for nervous complaints, lower abdominal … Another small trial supports a potential cholesterol benefit. This recipe contains lemon balm, an herb that some promising research indicates can boost mood and improve cognitive performance. [33] Get it as soon as Fri, Dec 4. This information is not specific medical advice and does not replace information you receive from your health care provider. Lemon balm cream has shown some efficacy in herpes virus lesions in a few small placebo-controlled trials. Much remains unknown about the bioavailability of lemon balm extracts and components. Benefits to mood, cognition, and memory also have been supported in vitro, with acetylcholinesterase (AChE) inhibition seen as especially relevant. The name Melissa corresponds to the Greek word for bee, while balm is a contraction of balsam. Lemon balm has antiviral activity against a variety of viruses, including herpes simplex virus (HSV) and HIV-1.11, 12 The activity has been attributed to caffeic acid and its di- and trimeric derivatives, as well as to tannins. Major mono- and sesquiterpenes include geranial, neral, beta-caryophyllene, beta-caryophyllene oxide, linalool, citronellal, nerol, and geraniol.3, 4, 5 R(+)-methyl citronellate is characteristic of Melissa oil and distinguishes it from lemon grass oil.6, 7 Flavonoids, oleanane, and triterpenes have also been isolated from the plant.4, 8 Major nonvolatile constituents are caffeic acid and its di- and trimeric derivatives, including rosmarinic acid and melitric acids A and B.7, 9, 10. None of this information is intended to replace the services of a qualified healthcare practitioner. It can be made into tinctures, dried, or made into tea fresh from the garden. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. 28 In vitro analyses of the antimicrobial properties of lemon balm suggested that at a concentration of 500microg/mL, the … We comply with the HONcode standard for trustworthy health information -. It is very interesting to read that, thanks so much, I will look out for the more colourful type as they are beautiful, as well as beneficial, so it is a winner through and through . Orange Essential Oil May Improve Symptoms of PTSD, “Organic Essential Oils,” USDA Organic Certification and Seal, PROBLEMS WITH USING ESSENTIAL OILS LIKE DRUGS, Safe and Effective Use of Essential Oils: What You Need to Know About What You’re Not Being Told, PROBLEMS WITH SELLING ESSENTIAL OILS LIKE DRUGS, Study Evaluates Seven Helichrysum Species for Volatile Profile and Essential Oil Composition, THE THEORY & PRACTICE OF ESSENTIAL OIL BLENDING, The Tranquility Oil; Vetiver Essential Oil. Essential oil created from the leaves can also eaten and used as an antioxidant (Marangui et al., 2004). Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). While lemon balm has been reported to be relatively well tolerated in humans when used for up to eight weeks, some adverse effects have been noted with both oral and topical administration. This information relates to an herbal, vitamin, mineral or other dietary supplement. Lemon balm’s cardiovascular, cytotoxic, anti-inflammatory, antinociceptive, hypoglycemic, hypolipidemic, antioxidant, antimicrobial, antiviral, antispasmodic, antiangiogenic, and antiepileptic effects all have support in various research models, with the general proviso that many doses used in animal trials cannot realistically be applied in clinical practice. SPL UNCLASSIFIED SECTION Gaia Herbs, Inc., 101 Gaia Herbs Drive, Brevard, NC 28712 Lemon balm {also called beebalm} comes in a variety of shades which are perfect in the herbal garden. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Obtained from fresh or dried flowers, leaves, and branches, LBEO is expensive due to its low yield; it comprises only 0.02-0.30% of plant material. Melissa is traditionally used as an adaptogen all around the world. The methanol extract was identified as a potent in vitro inhibitor of rat brain GABA transaminase (GABA-T), an enzyme target in the therapy of … 1 2 3 4 Enter your email address to follow this blog and receive notifications of new posts by email. Lemon balm (Melissa officinalis, Lamiaceae) is widely used in European traditional medicine and Iranian traditional medicine (ITM) for various diseases, as well as being consumed as a salad vegetable and food flavoring. FREE Shipping on orders over $25 shipped by Amazon. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. The essential oil made from lemon balm is high in compounds called triterpenes, which are rapidly absorbed through the lungs and have a calming effect on the body through aroma therapy. Primary interest in lemon balm surrounds its effects on the central nervous system. It’s also celebrated for its medicinal qualities. The leaves are harvested before flowering and used medicinally.1, Lemon balm has been used in herbal medicine since the times of Pliny (Roman, AD 23-79), Dioscorides (Greek, AD 40-90), Paracelsus (Austrian 1493-1541), and John Gerard (English, 1545-1612). Stress Relief. Much remains unknown about the bioavailability of lemon balm extracts and components. [7] [30] [31] [32] The composition and pharmacology and potential uses of lemon balm have been extensively studied, especially with regard to its traditional uses. In a series of trials investigating the effects of lemon balm extract on laboratory-induced stress, a dose-dependent effect was demonstrated for single doses of Melissa officinalis.2, 20, 21 Cholinergic receptor-binding properties have also been demonstrated.20 With 600 mg of extract, increased calmness and decreased alertness were demonstrated compared with placebo. If your life is governed by anxiety and stress, you can reap the benefits of lemon … In other words, … Contraindications have not yet been identified. No adverse events were reported.40, In patients with mild to moderate Alzheimer disease, 60 drops of lemon balm extract (citral 500 mcg/mL) increased cognitive function and decreased agitation over placebo.22, 23, 24 Essential oil of lemon balm applied to the faces of patients with dementia decreased agitation compared with placebo.25, 26, The contractility of rat ileum was reduced with essential oil of lemon balm and its citral extract.33 Babies with colic given a combination preparation containing lemon balm extract as well as 2 other extracts showed improved symptoms.34, Crude lemon balm herb typically is dosed at 1.5 to 4.5 g/day. lemon-scented herb known for its calming and anti-inflammatory effects The plant has culinary and medicinal uses, with principal historical medicinal uses being carminative, diaphoretic, and antipyretic.2, Lemon balm leaves contain 0.2% to 0.3% of a lemon-scented essential oil similar to that of lemon grass. Lemon balm supplements are made from the leaves of the plant. I grow and use lemon balm for tea or to use a part of a tea brew from the garden. Lemon balm is LIKELY SAFE when used in food amounts. Phenylpropanoids including hydroxycinnamic acid derivatives such as caffeic and chlorogenic acids and in particular rosmarinic acid (up to 6%) [ESCOP, 2003; WHO monograph s, 2002]. Lemon balm’s rosmarinic acid (RA) component, with four hydroxyl groups, may be a stronger antioxidant than vitamin E or Trolox. Pliny, Hippocrates, Galen, Culpepper, and even Shakespeare all spoke of its attributes. Lemon balm, including lemon balm extract, has been shown to improve sleep quality. Abstract Lemon balm (Melissa officinalis) has been used historically and contemporarily as a modulator of mood and cognitive function, with anxiolytic effects following administration of capsules, coated tablets and topical application. Chaparral, Now, More Than Ever, It’s Important to Stay Healthy at Home. Human clinical trials have shown that lemon balm can relieve agitation in people with dementia and improve the mood and stress levels of healthy adults. I like the contrast with borage. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The plant has culinary and medicinal uses, with principal historical medicinal uses being carminative, diaphoretic, and antipyretic.2 Similarly, mean AST decreased 1.35 units/L with treatment and increased 2.23 units/L with placebo. Lemon balm extract is a … Author information: (1)Department of Human Physiology and Pharmacology, Sapienza University, Rome, Italy. They have been admired for their beauty and fragrance, and, These two recipes are prepared as teas but are not taken in your tea cup – they help with the discomfort of flu season in, Copyright © Crooked Bear Creek Organic Herbs 2014-2020. Protects against heart and liver problems. Crooked Bear Creek Organic Herbs and Gardens Sustainability Stewardship, Aromatherapy with Damask Rose Essence Reduces Pain Caused by Treatment of Burn Injuries, Aromatherapy Healing ~ Aromatherapy Techniques, AROMATIC MEDICINE: INTERNAL DOSING OF ESSENTIAL OILS, Favorite Essential Oil Diffuser Blends For Autumn, All About the Uses and Benefits of Orange Oil, Anticancer Properties of Essential Oils and Other Natural Products, Create Inner Peace with Rose Geranium Oil, Geranium Essential Oil: Creating A Complete Balance. Lemon balm was used by Avicenna (981-1037) for all diseases caused by black phlegm and black bile. Not enough is known about the safety of lemon balm when used long-term. Medically reviewed by This is only a brief summary of general information about this product. It Can Calm You. Neuroprotective effects of various fractions of lemon balm have been demonstrated in vitro and in vivo, with significant protection against oxidative stress and amyloid beta (Aβ)-induced toxicity. Most clinical trials report no adverse reactions.2, 20, 37, Melissa extract was not found to be genotoxic in a screen of several medicinal plants.39. Let’s Create Some Herbal Remedies – When Cold and Flu Season Arrives. Last updated on Jul 20, 2020. With 300 mg, no modulation of stress was found, but speed and accuracy of mathematical processing increased.21 At the highest dosage of 1,600 mg, a paradoxically negative effect on mood resulted, with reduced alertness.20 Lemon balm 80 mg combined with valerian 160 mg taken for 1 month significantly improved sleep quality compared with baseline (P = 0.001) and placebo (P = 0.0001) in women experiencing sleep disruption/disorders subsequent to natural menopause. Sorry, your blog cannot share posts by email. Since 1984, it has been listed in the German Commission E monographs and is included in several pharmacopeias. Lemon balm Traditional medicine Biological activity Phytochemistry abstract Ethnopharmacological relevance: Melissa officinalis L. is a medicinal plant that has long been used in different ethno-medical systems especially in the European Traditional Medicine and the Iranian Tra-ditional Medicine for the treatment of several diseases. Pediatric patients have displayed improvement in restlessness and dyssomnia with the ingestion of lemon balm extract. Pharmacology, Biochemistry and Behavior, 72 (4), 953-964. Lemon balm has been used for medicine for thousands of years by many people in the Mediterranean. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Doses of 600 to 1,600 mg extract have been studied in trials. Thank you for such interesting posts. 95 ($1.25/Ounce) Save more with Subscribe & Save. Lemon balm has also been shown to possess antimicrobial, antiviral, antispasmodic and antitumoral properties. There are some who even contend that it can improve cogni… A 1% extract cream has been studied as a topical agent for treatment of herpes virus lesions. None of these products is intended to diagnose, treat, cure or prevent any disease. Mine is a different type I think as the flowers are not deep pink. Phenolic compounds in lemon balm, including derivatives of benzoic and caffeic acids, likely exert antioxidant and free radical scavenging effects. Lemon Balm Tea (Bulk Herbal Tea): Bulk Lemon Balm Leaf (Melissa Officinalis Caffeine Free) - Herbal Balm, Bulk Balm Leaf (Cut and Sifted), 1lb (16Oz) 4.5 out of 5 stars 102. Clinical trials generally report no adverse reactions. None of these statements has been evaluated by the Food and Drug Administration. Antibacterial/antifungal effects: The lemon balm constituent rosmarinic acid was reported to impair in vivo activation of mouse macrophages by heat-killed Corynebacterium parvum, as measured by the decreased capacity of the activated macrophages to undergo the oxidative burst. Lemon balm’s lemony flavor and aroma are due largely to citral and citronellal, although other phytochemicals, including geraniol (which is rose-scented) and linalool (which is lavender-scented), also contribute to lemon balm’s scent. This information should not be used to decide whether or not to take this product. The authors searched unpublished old texts and several databases of published literature to review the botanical characteristics, traditional uses, phytochemistry, pharmacology, pharmacokinetics, and toxicity of lemon balm. The lyophilized hydroalcoholic extract, which does not contain the volatile oil components, exhibited sedative activity in several mouse models when given intraperitoneally.19 This extract was also active in an acetic acid writhing analgesia assay but not in a hot plate test. A concentration-dependent inhibition of HSV-2 proliferation by lemon balm essential oil has been demonstrated, possibly due to the citral or citronellal components.13 Activity against bacteria and fungi has been evaluated with varying results.4, 8, 14 Activity against culex mosquito larvae has also been demonstrated.15, Placebo-controlled trials have shown symptomatic improvement for herpes virus lesions after application of a standardized lemon balm cream applied 2 to 4 times daily for 5 to 10 days.16, 17, 18, In vitro antioxidant activity has been described for lemon balm essential oil and its extracts.4, 10, 14, 30, Activity against human and mouse cancer cell lines has been demonstrated in vitro.5, In hyperlipidemic rats and mice, lemon balm extracts improved the lipid profile as well as liver enzyme markers (AST, ALT, alkaline phosphatase) and increased glutathione levels in the tissue.31, 32, A double-blind, randomized, placebo controlled trial (n=58) in borderline hyperlipidemic adults documented a significant improvement in low-density lipoprotein (LDL) cholesterol levels (P=0.022) as well as AST (P=0.009) with administration of M. officinalis leaf powder (500 mg 3 times daily for 2 months) compared to placebo. The placebo group in this randomized trial (n = 100) also experienced a significant improvement in sleep scores compared with baseline (P = 0.0001). Lemon balm has been traditionally used for different medical purposes as tonic, antispasmodic, carminative, diaphoretic, surgical dressing for wounds, sedative-hypnotic strengthening the memory, and relief of stress induced headache, but in modern pharmacology is value in the management of mild to moderate Alzheimer’s, A standardized preparation of lemon balm 80 mg and valerian extract 160 mg, Euvegal Forte, has been given 2 or 3 times/day as a sleep aid, and has also been studied in children.35, 36, 37 A 1% extract cream has been studied as a topical agent for herpes.17. Lemon balm is a low-growing perennial herb with ovate- or heart-shaped leaves that emit a lemon odor when bruised. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. Inactive ingredients Organic Glycerin, Organic Lemon Balm Extract, Organic Lemon Essential Oil, Purified Water USP. It is most often used in multiherb preparations, with varying dosages. One small study demonstrated decreased stress and agitation in patients with dementia and Alzheimer disease. Doses of 600 to 1,600 mg have been studied in trials. Koetter, U., & Biendl, M. (2010). Humulus lupulus: A review of its historic and medicinal … Crooked Bear Creek Organic Herbs abides by the National Association for Holistic Aromatherapy’s Code of Ethics.
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